With the growing amount of clinical research, regulations and research ethics are becoming more stringent. This trend introduces a need for quality assurance measures for ensuring adherence to research ethics and human research protection beyond Institutional Review Board approval. Audits, one of the most effective tools for assessing quality assurance, are measures used to evaluate Good Clinical Practice and protocol compliance in clinical research. However, they are laborious, time consuming, and require expertise. Therefore, we developed a simple auditing process and (...) evaluated its feasibility and effectiveness. The screening audit was developed using a routine audit checklist based on the Severance Hospital’s Human Research Protection Program policies and procedures. The measure includes 20 questions, and results are summarized in five categories of audit findings. We analyzed 462 studies that were reviewed by the Severance Hospital Human Research Protection Center between 2013 and 2017. We retrospectively analyzed research characteristics, reply rate, audit findings, associated factors and post-screening audit compliance, etc. Investigator reply rates gradually increased, except for the first year. The studies were graded as “critical,” “major,” “minor,” and “not a finding”, based on findings and number of deficiencies. The auditors’ decisions showed fair agreement with weighted kappa values of 0.316, 0.339, and 0.373. Low-risk level studies, single center studies, and non-phase clinical research showed more prevalent frequencies of being “major” or “critical”. Inappropriateness of documents, failure to obtain informed consent, inappropriateness of informed consent process, and failure to protect participants’ personal information were associated with higher audit grade. We were able to observe critical GCP violations in the routine internal audit results of post-screening audit compliance checks in “non-responding” and “critical” studies upon applying the screening audit. Our screening audit is a simple and effective way to assess overall GCP compliance by institutions and to ensure medical ethics. The tool also provides useful selection criteria for conducting routine audits. (shrink)

Giải quyết biến đổi khí hậu và ô nhiễm môi trường đang và sẽ là thách thức lớn của nhân loại trong thế kỷ 21. Con người không còn nhiều thời gian để sửa chữa, phục hồi đưa hệ sinh thái môi trường (tự nhiên) trở về trạng thái an toàn. Trong khi các nỗ lực trong thời gian qua chưa thực sự hiệu quả thì COP26 mở ra cơ hội lớn để nhân loại tiến gần đến mục tiêu kiềm (...) chế nhiệt độ của trái đất không vượt quá 1.5 độ C. Mặc dù Việt Nam cùng với 146 quốc gia trên thế giới đã có cam kết mạnh mẽ nhất trong việc giảm phát thải vào năm 2050, tuy nhiên việc cụ thể hóa cam kết thông qua các giải pháp sáng tạo là rất quan trọng. Sử dụng (áp dụng, vận dụng) hệ sáng tạo 3D và nguyên lý bán dẫn giá trị, tác giả đề xuất hệ sinh thái “giải pháp trụ cột” cần thực hiện gồm có tăng cường thông tin, truyền thông, nghiên cứu khoa học về môi trường (biến đổi khí hậu, ô nhiễm môi trường...); xây dựng, chuyển đổi và nâng cao văn hóa và môi trường; đẩy mạnh phát triển kinh tế gia tăng phúc lợi; xây dựng (chuyển đổi) lớp doanh nhân có văn hóa, trách nhiệm môi trường; tăng cường mở rộng sự hợp tác quốc tế về mọi mặt đặc biệt là trong lĩnh vực kinh tế, truyền thông và khoa học; và thực thi các giải pháp nêu trên một cách kỷ luật. (shrink)

Quan điểm về tính và nhân tính là một bộ phận trọng yếu của lý luận Tống Nho về con người. Lê Quý Đôn cũng dựa vào các lý luận về tính và nhân tính của Tống Nho để xây dựng quan điểm của mình về tính, tính người, tâm. Tuy nhiên, có điểm đặc biệt trong các quan niệm đó của Lê Quý Đôn: ông ít khi xem xét trực tiếp, hoặc có những phát biểu mang tính thuần tuý (...) lý luận về các vấn đề tính và nhân tính. Chỉ có thể bóc tách các quan điểm về tính và nhân tính của Lê Quý Đôn từ những luận bàn về chính trị, xã hội, v.v. tức là những vấn đề hiện thực và cụ thể. Điều này cho thấy tính thực tiễn trong lập trường của Lê Quý Đôn. Chính bởi lập trường đó, ông đã tránh được các hạn chế viển vông, hư huyễn và khép kín của Tống Nho, để rộng mở tiếp thu các luồng tri thức từ các lập trường khác, và hướng lý luận của mình vào các hoạt động hiện thực. (shrink)

Matti Eklund (2017) has argued that ardent realists face a serious dilemma. Ardent realists believe that there is a mind-independent fact as to which normative concepts we are to use. Eklund claims that the ardent realist cannot explain why this is so without plumping in favor of their own normative concepts or changing the topic. The paper first advances the discussion by clarifying two ways of understanding the question of which normative concepts to choose: a theoretical question about which concepts (...) have the abstract property of being normatively privileged and a further practical question of which concepts we are to choose even granting some concepts are thus privileged. I argue that the ardent realist’s best bet for answering the theoretical question while avoiding Eklund’s dilemma is to provide a real definition of this property. I point out the difficulties for providing such a definition. I then argue that even with an answer to the theoretical question, the ardent realist faces a further dilemma in answering the practical question. In sum, though I see no knock-down argument against ardent realism, it may nonetheless die a death by a thousand cuts. I close by considering a deeper reason for why ardent realism is so difficult to defend: every argument starts somewhere. It is unclear how there can be an Archimedean point that makes no reference to any normative concepts that can nonetheless be employed to convince everyone to adopt ours. I then briefly propose two options for someone still inclined towards realism: (i) accept that our normative concepts are normatively privileged without attempting to explain why this is so, or (ii) be less ardent and accept a perspective-dependent account of normativity. (shrink)

This volume, an assemblage of essays previously published in the Journal of Chinese Philosophy, conveniently and strategically brings together some of the trenchant interpretations and analyses of the salient, structural aspects of the philosophy of the Yijing. They reveal how the ancient Classic offers a graphically vivid and conceptually dynamic dramaturgy of the ways in which the natural world works in conjunction with the human one. Its cosmological architectonics and philosophical worldview continue to have enormous purchase on our current imagination, (...) even though readerly imperatives and responses have rendered this classic into a text of multiple significances, catering to pluralistic readerships and clienteles. Nonetheless, the essays in this volume lay bare some of the original authorly visions and insights of the Yijing, clearly showing that their apparent truthfulness to our cosmic and human conditions inspire philosophical and even theological questions. The Yijing's authorial designs of the eight trigrams and hexagrams, which encapsulate the primordial state of homo-cosmic phenomena and situations, together with the yin-yang forces and the dao, are taken for granted as integers in a grand universal equation, factored out to represent a ceaselessly changing cosmos in which heaven, earth and humanity commingle, such that the whole and unity can be found in the individual and the opposite, and vice versa. (shrink)

Although there has been significant work on aesthetic snobbery and its ethical implications, much less work has been done on the aesthetic normie (normie for short). The normie is someone who primarily engages with popular aesthetic items. I argue that the normie is motivated by a drive towards sociality to connect with others and to rely on them given limited resources and time. I argue that the normie who is motivated by this drive will limit their aesthetic range and depth. (...) This makes it harder for them to access new aesthetic experiences, distorts their ability to accurately appraise others, and makes it harder for them to connect with others. Nonetheless, I argue that we can achieve the goods of sociality by being aesthetically open. Expanding our willingness to engage with new aesthetic items and to develop and share more informed aesthetic judgments allows us to access more aesthetic values, appraise each other more accurately, and form valuable aesthetic communities. (shrink)

Human resource management in managing environmental, social, governance, or corporate social responsibility initiatives has been recently raised. Yet, little attention has been paid to integrating CSR and HRM. Our primary goal was to identify how and whether certain HR practices are critical for developing employee capability to operate in firms with active CSR initiatives. We first examine the impact of external CSR activities on firm-level work outcomes. Moreover, we attempt to identify a choice of particular HR practices that could be (...) aligned with external CSR activities. We then empirically examine how each HR practice interacts with external CSR activities that influence employee retention and labor productivity. Using three longitudinal datasets conducted by the government-sponsored research institution over 154 publicly traded Korean firms for five waves of survey years, the results show that external CSR has a limited impact on employee retention and labor productivity. However, when external CSR activities are combined with a specific set of HR practices, including person-organization fit-based selection, performance-based pay, extensive investment of training and development, and employee suggestion program, the impact of external CSR on employee work outcomes is more substantial. The results indicate that external CSR and a particular set of HR practices as internal CSR can be complementary and generate a positive interaction on creating sustainable human capabilities. (shrink)

Gemass ihrer grundlegenden Bedeutung wurde die Ousia- und Eidoslehre des Aristoteles uber viele Forschergenerationen hinweg intensiv diskutiert und steht immer noch im Mittelpunkt der Aristoteles-Forschung. Die Lehre bleibt jedoch nur einseitig interpretiert und verstanden. Ihre bisherige Interpretation hat sich allzu sehr auf die sogenannten Substanzbucher der Metaphysik beschrankt, ohne dabei den der Lehre wesentlichen biologischen Aspekten gebuhrende Beachtung zu schenken. Der Autor schliesst diese Forschungslucke. So wird im ersten Teil des Werkes Metaphysik Z, der Haupttext der Ousialehre, sorgfaltig kommentiert, und (...) im anschliessenden zweiten Teil werden unter Bezugnahme auf die im vorhergehenden Teil erorterte Problematik drei wichtigste biologische Schriften des Aristoteles besprochen. Dadurch wird ein wesentlicher Zusammenhang zwischen der Ousia- und Eidoslehre in der Metaphysik und der Biologie hergestellt. (shrink)

Unlike many commentators who tend to see Schweitzer's mission one-sidedly, I show the coexistence of liberal and conservative elements in his mission. While his mission intent was mostly motivated by the former, his mission practices largely show the latter. In this essay, I analyze them in detail in three parts. I first explain how such opposite elements can coexist by applying Dipesh Chakrabarty's notion of provincializing Europe. Like most nineteenth-century Western liberals, Schweitzer advocated Enlightenment rights for Europeans, but denied them (...) to the colonized. I then argue that Schweitzer's mission was motivated by the liberal elements of his theology. When his critical theology led him to deny the divinity of Jesus, he found a new basis for Christianity in Jesus? ethical activism, which led him to become a medical missionary to Africa. I then examine Schweitzer's conservative practices in Africa: by applying the developmental model of Hegelian-Marxist historicism to African society, Schweitzer opposed both decolonization and advanced learning to Africans. Schweitzer's missionary practices in Africa, I therefore conclude, were more conservative than those of the typical European missionary. (shrink)

This article presents how Paul, in 1 Thessalonians, executes the process of the formation of the Thessalonian community. Using the sociological concept of symbolic boundaries, it is argued that the resources – (1) the kerygmatic narrative, (2) the local narratives, and (3) the ethical norms – that Paul incorporates into the letter take an essential role to promote the converts to derive a cooperative identity from the community to which they belong and to strengthen the distinction between them and the (...) larger society. By providing internal consensus and external separation, the resources serve to construct and maintain the Thessalonian community that is internally united and externally distinct. (shrink)

Name der Zeitschrift: Neue Zeitschrift für Systematische Theologie und Religionsphilosophie Jahrgang: 59 Heft: 1 Seiten: 265-280.

Although any typology of constructivism might be arbitrary, there are, broadly speaking, two distinctive constructivist approaches in security studies as well as International Relations (IR) according to their different meta-theoretical stances: conventional constructivism, on the one hand, and critical constructivism on the other. Indeed, regarding how to understand state identity which is integral to national security, there has meta-theoretically been fierce contention between conventional and critical constructivist security studies. In not ignoring but slightly toning down this contention operating at the (...) abstract level, this article aims to present a pragmatic application of the two different (or conflicting) constructivisms to capturing a more complete picture of state identity formation in substantive empirical research of constructivist security studies. The pragmatic approach is that, without being immersed heavily in the meta-theoretical strife between the two seemingly conflicting constructivist camps, both constructivisms should be treated as different analytical frameworks for examining different (internal and external) faces of state identity formation: the external construction of state identity can be well addressed by conventional constructivism, while the internal one by critical constructivism. In this sense, the relationship between conventional and critical constructivism can be understood as not conflicting but complementary in empirical research, as both constructivisms enrich and deepen our understanding of state identity formation in different ways. (shrink)